A highly sensitive and selective enzymatic glucose sensor based on platinum nanoparticles embedded with acid treated reduced graphene oxide

In this work, a highly sensitive and selective electrochemical sensor was newly developed by using acetic acid treated reduced graphene oxide (acRGO) sheet decorated with platinum nanoparticles (PtNP), covalently bonded with enzyme composites, and coated with nafion for effectively urine glucose detection. The fabricated sensor showed excellent amperometric response to glucose recognition with a sensitivity of 69.44 μA/mMcm2, wide detection range of 0.002-12 mM, low detection limit of 0.002 mM (signal to noise ratio is 3), and a short response time of 4 s. In addition, the sensor exhibited negligible response characteristics against interference species, longtime stability, and acceptable performance of glucose detection in human urine.