Biological Data Acquisition for System Level Modeling—An Exercise in the Art of Compromise

This chapter contains section titled: 10.1 Chapter Overview, 10.2 The Estimated Size and Complexity of Intracellular Regulatory Networks, 10.3 Classifying Measurement Techniques from a Computational Modeling Perspective, 10.4 Low Throughput, Accurate Measurements of Gene Derivative Concentrations, 10.5 High Throughput Measurements and Low Accuracy—A Necessary Compromise?, 10.6 Detecting Regulatory Interactions and Quantifying Kinetic Parameters, 10.7 Population Averaged versus Single Cell Measurementsm, 10.8 Conclusions: A Final Look at Experimental Design