http://ieeexplore.ieee.org TOC Alert for Publication# 7728 2013 June 18 12 2 C1 C1 172 12 2 C2 C2 149 ${rm Fe}_{3}{rm O}_{4}$ magnetic nanoparticles bio-functionalized with antibodies against CRP, dispersed in pH-7.4 phosphate buffered saline solution. Several key factors of the reagent, such as particle concentration, volume ratio of reagent to sample, and particle size, are manipulated to optimize the LLD of detecting CRP.]]> 12 2 65 68 458 ${rm MS2DB}+$ is an open-source platform-independent web application for determining, in polynomial time, the disulfide linkages in proteins using tandem mass spectrometry (MS/MS) data. It utilizes an efficient approximation algorithm which allows the consideration of multiple ion-types ( $a$, $a_{o}$, $a^{ast}$, $b$, $b_{o}$, $b^{ast}$, $c$, $x$, $y$ , $y_{o}$ , $y^{ast}$ , and $z$ ) in the analysis. Once putative disulfide bonds are identified, a graph optimization approach is used to obtain the most likely global disulfide connectivity pattern. Availability—http://haddock2.sfsu.edu/~ms2db/disulfidebond/]]> 12 2 69 71 383 $-$25.4 mV, and 49.07 ${rm m}^{2}$ and 27.12% respectively, while the melting point was 4.3 $^{circ}{rm C}$ lower than of HPO. Unlike in serum-free, NLC incubated in fetal bovine serum-supplemented medium did not show particle growth, suggesting that serum proteins in medium inhibit nanoparticles aggregation. The study also showed that NLC was less toxic to BALB/c 3T3 cells than Polysorbate 80. Thus, NLC with olive oil, HPO, and Polysorbate 80 as components are potentially good drug carriers with minimal cytotoxicity on normal cells.]]> 12 2 72 78 697 12 2 79 92 2761 12 2 93 97 530 12 2 98 105 1586 12 2 106 111 1000 12 2 112 118 1441 12 2 119 127 1923 12 2 128 134 1983 12 2 135 137 504 12 2 138 138 2541 12 2 139 139 258 12 2 140 140 1156 12 2 C3 C3 80 12 2 C4 C4 5