A wireless interstitial pressure sensor with a Guyton chamber

In this paper, we present a wireless interstitial fluid pressure sensor incorporating a perforated chamber first introduced by A. C. Guyton. The Guyton chamber allows for an accurate measurement of IFP without the interference from various cellular components by permitting the interstitial fluid to penetrate the chamber after implantation. The sensor consists of a coil, an air chamber, a silicone membrane embedded with a nickel plate, and a Guyton chamber. The fabricated device is 6 mm in diameter and 1 mm in thickness. The measured sensitivity is 20 kHz/mmHg from -5 to 15 mmHg.