UVa/Padova T1DMS dynamic model revision: For embedded model control

A revision of the dynamic equations on which the UVa/Padova Type 1 diabetes metabolic simulator is based, is presented with special attention to the oral glucose absorption and the static glucagon secretion models. Slightly modifications are proposed and validated using the version 3.2 of the simulator and in-house versions of the dynamic equations found in literature. The emptying rate for the oral absorption model is modified taking into account the size of the meals, while a continuous state-space model of the glucagon secretion model suitable for embedded model control design is presented. The achieved overall relative model error in the plasma glucose is less than 2.5% for 10 virtual patients available in this FDA approved commercial simulator.