Architecture and procedures for pH and temperature monitoring in medical applications

Temperature (T) and pH variations affect the function of electrochemical sensors. The study of their effects on point-of-care medical sensors is vital due to their delicate use. An example comes from anesthesia where difficult-to-dose drugs are infused in patient's blood, e.g. propofol. In this case, a drug concentration monitoring system is required. However, blood pH and T can vary during anesthesia, with respect to the patient's clinical situation. A portable, low-cost and easy-to-reproduce Printed Circuit Board (PCB) is here designed for the first time up to now for anesthesia, in order to continuously keep under control pH and T variations while a dedicated system constantly monitors the drug level. The board is driven by a Raspberry Pi (RPi). Measurements in different pH and T conditions validated the proposed system.