CyberCardia project: Modeling, verification and validation of implantable cardiac devices

In this paper, we survey recent progress in CyberCardia project, a CPS Frontier project funded by the National Science Foundation. The CyberCardia project will lead to significant advances in the state of the art for system verification and cardiac therapies based on the use of formal methods and closed-loop control and verification. The animating vision for the work is to enable the development of a true in silico design methodology for medical devices that can be used to speed the development of new devices and to provide greater assurance that their behavior matches designer intentions, and to pass regulatory muster more quickly so that they can be used on patients needing their care. The acceleration in medical-device innovation achievable as a result of the CyberCardia research will also have long-term and sustained societal benefits, as better diagnostic and therapeutic technologies enter into the practice of medicine more quickly.