Effects of color spaces to the cell segmentation in histopathological images

With the progressive development of the computer-aided diagnosis (CAD) systems, analysis of high resolution histopathological images has become more easier. In the proposed study, the effects of different color spaces used in various studies in the literature are investigated for the discrimination of cellular structures from background in histopathological images. For this purpose, performances of k-means, fuzzy c-means and expectation-maximization algorithms are compared in different color spaces. In the experimental results section, different segmentation accuracy metrics are presented in comparative manner.