Impact of surface properties of blends based on quatemized polysulfones on modeling and interpretation the interactions with blood plasma: Quaternized polysulfones blends interactions with blood plasma

Hydrophilic/hydrophobic character along with the adhesion properties of blood components and plasma proteins for the quaternized polysulfone (PSFQ)/polyvinyl alcohol (PVA) blends were analyzed in order to use these systems in biomedical applications. It was observed that, the obtained results are influenced both the chemical structures of blend components as well as by their mixing ratio. In this context, an important role has the repulsive electrostatic interactions generated by the charge groups of quaternized polysulfone that establish its less hydrophilic nature, comparatively with polyvinyl alcohol. In terms of biological material adhesion to the polysulfones substrate has been observed that for samples with a more significant hydrophilic character, namely PVA and PSFQ/PVA blends with higher content of PVA the interaction with blood plasma are pronounced. The relationship between the different physical and chemical characteristics of these blends and their biocompatible properties was established for maximizing the selectivity and performance of these materials for biomedical applications.