Joint registration of attenuation and activity images in gated TOF-PET

To date, attenuation correction of gated PET emission data remains a challenge. Joint activity and attenuation estimation methods may contribute to solving this challenge. In this work, we demonstrate a framework in which the gated PET activity and attenuation images are jointly reconstructed and then registered to a reference frame by a joint registration approach. The method is studied and compared to common approaches by means of 2D and 3D simulations.