Dynamic Recording ECG for Ischemic Rat Heart Using Implantable Wireless Telemetry

Establishment of unique animal model to be able to evaluate the structural and functional improvement dynamically after myocardiac infarction (MI) is curtail for developing novel therapy for functional regeneration of infarcted myocardium. In this study, we used the wireless implantable telemetry to monitor the ECG of MI rat under normal activity and treadmill training dynamically. The results of this study show that the in vivo implantable ECG recording technique is able to record the ECG of LAD-ligated heart under normal activity and treadmill training. The model established in this study will be a powerful system for us to evaluate the improvement of infarcted myocardium in structural and functional dimension.