Differential Equations Systems versus Scale Free Networks in Sepsis Modeling

The paper proposes a comparison between models that relieves the characteristics of the patient evolution in sepsis as the result of correct or corrupted information transfer as the cell level. Specifically, two different models for the cellular interactions are compared - one based on a three variables system of differential equations, the other on a cellular interaction scale free network. The advantages and limits of each model in understanding the structure of cellular signaling networks involved in sepsis phenomena are finally discussed