Strong Coupling System for the LV Motion Simulation in a Distributed Simulation Environment

A system where model parts can be easily exchanged and modified is of great advantage, especially in a combination of models such as an electrophysiological cell model and a mechanical model to a more complex left ventricular (LV) motion model. The use of a distributed simulation environment is straightforward because each simulation model is calculated by an existing user-friendly simulator. However, the weak coupling calculation usually used in a distributed environment reduces the accuracy of the simulation and results in an unstable simulation of the LV motion. To overcome this problem, we have developed a strong coupling simulation system for the distributed simulation environment. Simulation results for a myocardial tissue and a simple LV shape model are presented to elucidate the effectiveness of our system.