Hough transform based peak detection: computer-assisted resonance assignments in NMR spectroscopy (protein study)

A Hough-transform-based method for locating peaks in NMR spectra is described. This method has been applied to four 2-D slices of the 3D-NMR spectrum. The program was able to identify all the peaks. This procedure is more robust than simple peak picking of local maxima since there is no false peak identification; however, there is a problem of multiple detection of peaks within the range of peak width.<
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