Instrumentation for simultaneous detection of low field NMR and biomagnetic signals

We have built and demonstrated a simple system with open geometry that measures biomagnetic signals such as magnetoencephalogram (MEG), magnetocardiogram (MCG) and magnetomyogram (MMG) simultaneously with low field nuclear magnetic resonance (NMR) free induction decay signals (FID). The system employs LT/sub C/ SQUID gradiometers and can operate with proton Larmor frequency in the 80 Hz-10 kHz range. A pre-polarizing field of up to 60 mT is generated by resistive coils. Two different types of SQUID gradiometers were used: a tangential thin-film planar first-order gradiometer and an axial second-order gradiometer. The gradiometers were placed inside a fiberglass dewar at about 1 cm distance from a subject. All measurements were performed inside a single-layer magnetic shielded room. This system is the prototype for a system that will ultimately be capable of measuring biomagnetic signals together with magnetic resonance images (MRI).