Frequency domain analysis of heart rate variability in sleep disordered breathing

Frequency domain analysis of the R-R intervals was performed in subjects with and without sleep disordered breathing (SDB). Data from Physionet's Apnea-ECG database as well as data collected at our sleep disorders clinic were used for this study. 15-minute ECG epochs were selected from polysomnography data. Power spectrum analysis of the resampled R-R interval series (1.2 Hz) was performed using Welch's averaged periodogram method. Normalized power in two bands, AB/sub 1/ (0.019 to 0.071 Hz) and AB/sub 2/ (0.019 to 0.036 Hz) were used to compare the impact of SDB events on the spectrum of R-R intervals. Normalized AB/sub 1/ power produced a sensitivity of 76% and a specificity of 100% in the data from the Apnea-ECG database. The same parameter produced a sensitivity of 76% and specificity of 52% in the data collected at our sleep laboratory. This difference in the results may be attributed to the severity and duration of SDB events present in the two datasets.