A fully integrated biosensor array for measurement of metabolic parameters in human blood

This paper presents a fully integrated biosensor array, which includes an oxygen sensor and a glucose sensor, for measurement of metabolic parameters in human blood. Partial oxygen concentration and glucose concentration in human blood were successfully detected in less than one minute using the developed biosensor array. Total sensor design is based on low melting point gel-based solid electrolyte that simplified fabrication process. Most parameters that are relative to sensor performance were calibrated and compared to optimize the sensor design. Such parameters include membrane material, thickness of membrane and solid electrolyte layer, area of electrodes, distance between electrodes, and the shape of electrodes. We also integrated the developed biosensor array with microfluidic systems for precise control of sample delivery.