Measuring the cortical thickness [MRI segmentation procedure]
Kruggel, F.; Yves von Cramon, D.
Mathematical Methods in Biomedical Image Analysis, 2000. Proceedings. IEEE Workshop on
Volume , Issue , 2000 Page(s):154 - 161
Digital Object Identifier 10.1109/MMBIA.2000.852372
Summary:Besides normal aging, a number of brain diseases are known to
reduce the amount of grey matter in the brain. To better understand the
nature and progression of these disease processes, quantitative
measurements of relevant brain structures, such as the regional cortical
thickness, are highly desirable. Starting from high resolution
volumetric MR images of the human head, a reliable segmentation
procedure for the grey matter compartment is described which allows
thickness measurements at sub-voxel resolution. Simulation experiments
and comparisons with published data from histological examinations prove
the validity of results
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