The intravenous route to blood glucose control
Parker, R.S.; Doyle, F.J., III; Peppas, N.A.
Engineering in Medicine and Biology Magazine, IEEE
Volume 20, Issue 1, Jan/Feb 2001 Page(s):65 - 73
Digital Object Identifier   10.1109/51.897829
Summary:This article discusses closed-loop blood glucose regulation algorithms that use the intravenous route for insulin delivery to insulin-dependent diabetic patients. Classical control methods and advanced algorithms using implicit knowledge or explicit models (empirical, fundamental, or “gray-box”) of the diabetic patient are examined. Current research on characterizing patient variability is presented, in the context of a model predictive controller able to adjust to changes in patient glucose and insulin sensitivity

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