A High-Density Magnetoresistive Biosensor Array with Drift-Compensation Mechanism
Shu-Jen Han; Heng Yu; Murmann, B.; Pourmand, N.; Wang, S.X.
Solid-State Circuits Conference, 2007. ISSCC 2007. Digest of Technical Papers. IEEE International
Volume , Issue , 11-15 Feb. 2007 Page(s):168 - 594
Digital Object Identifier 10.1109/ISSCC.2007.373347
Summary:A DNA microarray of 1008 magnetoresistive sensors employing multidivided array structures for detecting either tow concentration or large-scale gene information is integrated with a 0.25mum BiCMOS chip. The input-referred noise is below 55nV/radicHz. Ionic solution interferences and drifts during biological reaction are removed by applying an in-plane AC magnetic field with two DC field states. Parallel readout is realized by combining FDM with TDM.
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