MIGRATION AND PROLIFERATION ANALYSIS FOR BLADDER CANCER CELLS
Said, A.F.; Karam, L.J.; Berens, M.E.; Lacroix, Z.; Renaut, R.A.
Biomedical Imaging: From Nano to Macro, 2007. ISBI 2007. 4th IEEE International Symposium on
Volume , Issue , 12-15 April 2007 Page(s):320 - 323
Digital Object Identifier 10.1109/ISBI.2007.356853
Summary:This paper presents a cell evolution analysis (CEA) scheme for bladder cancer cells. The proposed scheme consists of a cell migration analysis component for computing the overall migration rate of the cell cluster, and a cell proliferation analysis component based on counting the individually segmented cells within the cell cluster at different time points. The proposed CEA scheme performs well for images with poor contrast and high cell concentrations, even when the cells are overlapping and small. Results are presented to illustrate the performance of the proposed scheme
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