An Effective Interwoven Loop Design Application for Two-Channel Microarray Experiments
Pirooznia, M.; Rawat, A.; Yang, J.Y.; Yang, M.Q.; Ping Gong; Perkins, E.J.; Youping Deng
Bioinformatics and Bioengineering, 2007. BIBE 2007. Proceedings of the 7th IEEE International Conference on
Volume , Issue , 14-17 Oct. 2007 Page(s):187 - 191
Digital Object Identifier   10.1109/BIBE.2007.4375563
Summary:Microarray technology is widely applied to address complex scientific questions. However, there remain fundamental issues of how to design experiments to ensure that the resulting data enables robust statistical analysis. Interwoven loop design has several advantages over other designs. However it suffers in the complexity of design. We have implemented an online web application which allows users to find optimal loop designs for two-color microarray experiments. Given a number of conditions (such as treatments or time points) and replicates, the application will find the best possible design of the experiment and output experimental parameters. It is freely available from http://mcbc.usm.edu/iloop.

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